Succinylcholine

  • Ditalin
  • Scoline
  • Anectine
  • Diacetylcholine
  • Suxemethonium
Formula
C14H30N2O4
Structure
Description
Odorless, white, slightly bitter powder.
Uses
Medication, veterinary medication.

Registry Numbers and Inventories.
CAS
306-40-1
RTECS
GA7000000
RTECS class
Drug; Human Data
Beilstein/Gmelin
1805311
Beilstein Reference
4-04-00-01451

Properties.
Formula
C14H30N2O4
Formula mass
290.46
Melting point, °C
243 - 245
Solubility in water
Very soluble

Hazards and Protection.
Storage
Store in a tightly sealed container, in a cool dry location. Solutions should be refrigerated.
Decomposition
When heated to decomposition, material emits toxic fumes of NOx.

Fire.

Health.
Exposure effects
Inadvertent overdose or administration of succinylcholine to patients deficient in pseudocholinesterase may result in apnea followed by respiratory arrest, hypotension followed by cardiovascular collapse.

First aid
 
   Ingestion
Intubate and ventilate as clinically indicated. Most patients with recover if adequate airway, ventilation and oxygenation are established rapidly. Seek immediate medical attention.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists. See Ingestion.
   Eyes
Irrigate eye for at least 20 minutes with water or saline. If irritation persists, seek medical attention. See Ingestion.

Transport.