Succinylsulfathiazole

  • 2-(N4-Succinylsulfanilamido)thiazole
  • 4'-(2-Thiazolylsulfamoyl)succinanilic acid
  • Sulfenterone
  • Butanoic acid, 4-oxo-4-[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]-
  • Thiacyl
  • Cremosuxidine
Formula
C13H13N3O5S2
Structure
Uses
Sulfonamid class antibiotic.

Registry Numbers and Inventories.
CAS
116-43-8
EC (EINECS/ELINCS)
204-141-0
22 36/37 45
RTECS
WM4767000
RTECS class
Drug; Natural Product
Merck
12,9046
Beilstein/Gmelin
349989
Beilstein Reference
4-27-00-04637
Canada DSL/NDSL
DSL
Austrailia AICS
Listed

Properties.
Formula
C13H13N3O5S2
Formula mass
355.4
Melting point, °C
187 - 193
Solubility in water
Very soluble
pKa/pKb
4.51 (pKa)
Partition coefficient, pKow
0.74

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. May cause sensitization by inhalation and skin contact. Target organ(s): Kidneys. Blood.
   Ingestion
May be harmful if swallowed.
   Inhalation
May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.