Sulfadimethoxine

  • Dimethoxysulfadiazine
  • 4-Sulfa-2,6-dimethoxypyrimidine
  • 6-Sulfanilamido-2,4-dimethoxy-1,3-diazine
  • 2,4-Dimethoxy-6-sulfanilamido-1,3-pyrimidine
  • 4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide
  • 4-(p-Aminobenzenesulfonamido)-2,6-dimethoxypyrimidine
Formula
C12H14N4O4S
Structure
Description
White, almost tasteless and odorless powder.
Uses
Veternary antibiotic effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

Registry Numbers and Inventories.
CAS
122-11-2
EC (EINECS/ELINCS)
204-523-7
36/37/38 43
26 36/37
RTECS
WO9030000
RTECS class
Drug; Reproductive Effector
Merck
12,9073
Beilstein/Gmelin
306856
Beilstein Reference
5-25-13-00290
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C12H14N4O4S
Formula mass
310.33
Melting point, °C
202 - 204
Boiling point, °C
549
Vapor pressure, mmHg
4E-12 (25 C)
Density
1.654 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
6.21 (pKa)
Heat of vaporization
82.8 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store at 2-8 C
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Flash Point,°C
286
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
1
 

Health.
Exposure effects
Irritant. Irritating to eyes, respiratory system and skin. May cause sensitization by skin contact. Target organ(s): Blood. Kidneys.
   Ingestion
May be harmful if swallowed.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
Causes skin irritation. May be harmful if absorbed through the skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water.
   Eyes
In case of contact, immediately flush eyes with copious amounts of water for at least 15 minutes.

Transport.