Sulfanilamide

  • f-1162
  • Albexan
  • Albosal
  • Ambeside
  • p-Aminobenzenesulfamide
  • 4-Aminobenzenesulfonamide
Formula
C6H8N2O2S
Structure
Description
White powder.
Uses
Medication.

Registry Numbers and Inventories.
CAS
63-74-1
EC (EINECS/ELINCS)
200-563-4
S 22 24/25
RTECS
WO8400000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Natural Product
Merck
12,9094
Beilstein/Gmelin
511852
Beilstein Reference
4-14-00-02658
EPA OPP
77902
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H8N2O2S
Formula mass
172.21
Melting point, °C
163 - 167
Boiling point, °C
401
Vapor pressure, mmHg
1E-6 (25 C)
Density
1.46 g/cm3
Solubility in water
7.5 g/L at 25 C
Refractive index
1.5897 (158 C)
pKa/pKb
10.10 (pKa)
Partition coefficient, pKow
-0.62
Heat of fusion
23.3 kJ/mol
Heat of vaporization
63.1 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides May react with azo and diazo compounds to generate toxic gases.
Decomposition
Nitrogen oxides, carbon monoxide, oxides of sulfur, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
196
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.

Health.
Exposure effects
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion. May cause reproductive and fetal effects.
   Ingestion
May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood.
   Inhalation
May cause methemoglobinemia, cyanosis, convulsions, tachycardia, dyspnea, and death. May cause respiratory tract irritation. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown blood.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2935 00 90