Suprofen

  • p-(2-Thenoyl)hydratropic acid
  • Maldocil
  • a-Methyl-p-(2-thenoyl)phenylacetic acid
  • Benzeneacetic acid, a-methyl-4-(2-thienylcarbonyl)-, (±)-
Formula
C14H12O3S
Structure
Uses
Ophthalmic non-steroidal anti-flammatory.

Registry Numbers and Inventories.
CAS
40828-46-4
EC (EINECS/ELINCS)
255-096-9
23/24/25 40
22 36/37/39 45
RTECS
MU6647000
RTECS class
Drug; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
2811
Merck
12,9180
Beilstein/Gmelin
1430606
Beilstein Reference
5-16-08-00403

Properties.
Formula
C14H12O3S
Formula mass
260.31
Melting point, °C
124
Boiling point, °C
443
Vapor pressure, mmHg
1E-8 (25 C)
Density
1.37 g/cm3
Solubility in water
Soluble
pKa/pKb
4.07 (pKa)
Heat of vaporization
73.8 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Sulfur oxides.

Fire.
Flash Point,°C
222
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Toxic. Toxic by inhalation, in contact with skin and if swallowed. Limited evidence of a carcinogenic effect. Target organ(s): Kidneys. Possible teratogen.
   Ingestion
See Inhalation.
   Inhalation
TOXIC; inhalation, ingestion, or skin contact with material may cause severe injury or death. Effects of contact or inhalation may be delayed.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
III