Temazepam

  • Crisonar
  • Cerepax
  • 7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one (IUPAC)
  • 1,3-Dihydro-7-chloro-3-hydroxy-1-methyl-5-phenyl-2H-1,4-benzodiazepin-2-one
Formula
C16H13ClN2O2
Structure
Uses
Hypnotic. US DEA Schedule IV.

Registry Numbers and Inventories.
CAS
846-50-4
EC (EINECS/ELINCS)
212-688-1
RTECS
DF1225000
RTECS class
Tumorigen; Drug; Human Data
Merck
12,9285
Beilstein/Gmelin
759300
Beilstein Reference
5-25-02-00242
Canada DSL/NDSL
DSL
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C16H13ClN2O2
Formula mass
300.74
Melting point, °C
159 - 160
Boiling point, °C
550
Vapor pressure, mmHg
6E-13 (25 C)
Solubility in water
Insoluble
pKa/pKb
11.84 (pKa)
Heat of vaporization
87.3 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Flash Point,°C
286
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. Harmful if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
Material may be irritating to mucous membranes and upper respiratory tract. May be harmful if inhaled.
   Skin
May cause skin irritation. May be harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.