Terephthalic acid

  • p-Phthalic acid
  • 1,4-Benzenedicarboxylic acid
Formula
C8H6O4
Structure
Description
White or off-white crystals or powder. Odorless or a slight acetic acid odor.
Uses
As a reagent for alkali in wool, additive to poultry feeds.

Registry Numbers and Inventories.
CAS
100-21-0
EC (EINECS/ELINCS)
202-830-0
R 36/37/38
RTECS
WZ0875000
RTECS class
Drug; Mutagen; Primary Irritant
Merck
12,9306
Beilstein/Gmelin
1909333
Beilstein Reference
4-09-00-03301
Swiss Giftliste 1
G-2909
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H6O4
Formula mass
166.13
Boiling point, °C
392
Vapor pressure, mmHg
7E-7 (25 C)
Saturation Concentration
Very low at normal temperatures.
Evaporization number
Probably very low at normal temperatures.
Density
1.472 g/cm3
Solubility in water
2.8 g/L
pKa/pKb
3.51 (pKa)
Partition coefficient, pKow
2.00
Heat of vaporization
67.7 kJ/mol
Heat of combustion
-3189 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a cool, dry, well-ventilated area away from incompatible substances.
Insufficient information
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents
Decomposition
Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Fire.
Flash Point,°C
260 (open cup)
Autoignition, °C
678
Upper exp. limit, %
7.7
Lower exp. limit, %
1.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Water or foam may cause frothing. Use carbon dioxide or dry chemical.
Fire potential
This material is probably combustible.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
5
Exposure effects
Decreased blood pressure has been reported in dogs. Human data are lacking. Neuroendocrine changes have been noted in exposed rats. Human data are lacking. <br>Rats exposed to aerosols by inhalation did not develop significant toxic effects in the dams or fetuses, and no teratogenic effects were observed. <br>&nbsp;&nbsp;&nbsp;1. Terephthalic acid was transported across the placenta; however, the concentrations in fetal tissues were LOW compared to those in maternal tissues. <br>No data were available to assess the potential effects of exposure to this agent during lactation.
   Ingestion
May cause irritation of the digestive tract.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes slight skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
4. Organic acids
HS Code
2917 36 00