Tetracycline hydrochloride

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  • Cyclopar
  • Polycycline hydrochloride
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  • 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
Formula
C22H24N2O8.ClH
Structure
Description
Crystals or fine bright yellow powder.

Registry Numbers and Inventories.
CAS
64-75-5
EC (EINECS/ELINCS)
200-593-8
RTECS
QI9100000
RTECS class
Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Natural Product
Beilstein/Gmelin
3844873
Beilstein Reference
4-14-00-02625
EPA OPP
6307
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C22H24N2O8*ClH
Formula mass
480.94
Melting point, °C
223
Decomposition point, °C
213
Solubility in water
Soluble

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Do not expose to air. Store protected from moisture. Store protected from light. Store under an inert atmosphere.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Store protected from light. Handle under an inert atmosphere. Store protected from air. Do not allow contact with water. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation. Place under an inert atmosphere. Do not get water inside containers.
Stability
Stable under normal temperatures and pressures. Substance undergoes color change upon exposure to light and air.
Incompatibilities
Air, moisture, oxidizing agents.
Decomposition
Hydrogen chloride, nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution. Extinguishing media: Use agent most appropriate to extinguish fire. Do NOT get water inside containers. In case of fire, use carbon dioxide, dry chemical powder or appropriate foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
May cause fetal effects.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. Substance may cause hypersensitivity reactions and liver, teeth and bone
   Inhalation
Excessive inhalation may cause minor respiratory irritation. May cause effects similar to those described for ingestion.
   Skin
May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid if irritation develops or persists. Wash clothing before reuse. Flush skin with plenty of soap and water.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.