Tetrahydropyran

  • Oxane
Formula
C5H10O
Structure
Description
Colorless, mobile liquid. Pungent, sweetish odor.

Registry Numbers and Inventories.
CAS
142-68-7
EC (EINECS/ELINCS)
205-552-8
R 11 19
S 16 29 33
UN (DOT)
1993
Merck
12,9356
Beilstein/Gmelin
102436
Beilstein Reference
5-17-01-00064
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed

Properties.
Formula
C5H10O
Formula mass
86.13
Melting point, °C
-44.2
Boiling point, °C
88
Vapor pressure, mmHg
70 (25 C)
Vapor density (air=1)
4.0
Density
0.881 g/cm3 (20 C)
Solubility in water
80 g/L
Viscosity
8.75 cp (20 C)
Refractive index
1.4211 (20 C)
Partition coefficient, pKow
0.89
Heat of fusion
1.78 kJ/mol
Heat of vaporization
31.5 kJ/mol

Hazards and Protection.
Storage
Keep away from sources of ignition. Do not store in direct sunlight. Store in a tightly closed container. Flammables-area. Regularly check inhibitor levels to maintain peroxide levels below 1%. Do not break the seal on the container until it is needed. Label the container with the date it was first opened. Long-term storage is not recommended.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. If peroxide formation is suspected, do not open or move container. Avoid contact with air and sunlight. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Unused chemicals should not be returned to the container. Do not distill since this removes peroxide-inhibitors.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves and clothing to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Isolate area and deny entry. Provide ventilation. Place under an inert atmosphere. Do not use combustible materials such as paper towels to clean up spill. A vapor suppressing foam may be used to reduce vapors.
Stability
Stable under normal temperatures and pressures. On long term storage, substances with similar functional groups form explosive peroxides. Explosive peroxides may form on concentration. Tends to form explosive peroxides; especially when anhydrous. Peroxide formation may occur in containers that have been opened and remain in storage.
Incompatibilities
Oxidizing agents, strong acids.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
-16
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. May form explosive peroxides. May accelerate burning if involved in a fire. Containers may explode when heated. Runoff from fire control or dilution water may cause pollution. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. Water may be ineffective. Do NOT use straight streams of water. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames.
Hazards
Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
2
 
Flammability
3
 
 
Reactivity
1
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause cardiac disturbances. Ingestion of large amounts may cause CNS depression.
   Inhalation
May cause respiratory tract irritation. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. May cause cardiac abnormalities. May cause burning sensation in the chest.
   Skin
May cause skin irritation and possible burns. May cause cyanosis of the extremities.
   Eyes
May cause blindness. May cause permanent corneal opacification. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1993
Response guide
Hazard class
3
Packing Group
I; II; III