Tetramethyl succinonitrile

  • TMSN
  • Tetramethylbutanedinitrile
  • Tetramethylsuccinic acid dinitrile
Formula
C8H12N2
Structure
Description
White crystals.

Registry Numbers and Inventories.
CAS
3333-52-6
RTECS
WN4025000
RTECS class
Reproductive Effector
Beilstein/Gmelin
1752813
Beilstein Reference
4-02-00-02054
Swiss Giftliste 1
G-2926
Canada DSL/NDSL
DSL
New Zealand
Listed

Properties.
Formula
C8H12N2
Formula mass
136.22
Melting point, °C
172
Boiling point, °C
264
Vapor pressure, mmHg
0.01 (25 C)
Vapor density (air=1)
4.7
Density
1.07 g/cm3
Solubility in water
Insoluble
Partition coefficient, pKow
0.40
Heat of fusion
6.9 kJ/mol
Heat of vaporization
50.2 kJ/mol
Heat of combustion
-4881 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Should a spill occur while you are handling this chemical, you should dampen the solid spill material with alcohol, then transfer the dampened material to a suitable container. Use absorbent paper dampened with alcohol to pick up any remaining material. Seal the absorbent paper, and any of your clothes, which may be contaminated, in a vapor-tight plastic bag for eventual disposal. Solvent wash all contaminated surfaces with alcohol followed by washing with a strong soap and water solution. Do not reenter the contaminate area until the Safety Officer (or other responsible person) has verified that the area has been properly cleaned.
Stability
No data.
Incompatibilities
Incompatible with acids; mixing nitriles with strong oxidizing acids can lead to extremely violent reactions Incompatible with other oxidizing agents such as peroxides and epoxides Can react vigorously with reducing agents Can react violently with (LiAlH4 + H2O).

Fire.
Flash Point,°C
116
Fire fighting
Fires involving this compound should be controlled with a dry chemical, carbon dioxide or Halon extinguisher.
Fire potential
This material is probably combustible.
Health
3

Health.
Exposure limit(s)
TLV: 0.5 ppm; 2.8 mg/m3 as TWA (skin) (ACGIH 1991-1992). OSHA PEL: TWA 3 mg/m3 (0.5 ppm) skin NIOSH REL: TWA 3 mg/m3 (0.5 ppm) skin NIOSH IDLH: 5 ppm
Poison_Class
2
Exposure effects
   Ingestion
See inhalation.
   Inhalation
Symptoms: headache, nausea; convulsions, coma; liver, kidney, gastrointestinal effects Target Organs: central nervous system, liver, kidneys, gastrointestinal tract .
   Skin
See inhalation.
   Eyes
See inhalation.

First aid
 
   Ingestion
If the victim is conscious and not convulsing, give 1 or 2 glasses of water to dilute the chemical and IMMEDIATELY call a hospital or poison control center. MMEDIATELY transport the victim to a hospital.
   Inhalation
IMMEDIATELY leave the contaminated area; take deep breaths of fresh air. IMMEDIATELY call a physician and be prepared to transport the victim to a hospital even if no symptoms (such as wheezing, coughing, shortness of breath, or burning in the mouth, throat, or chest) develop. Provide proper respiratory protection to rescuers entering an unknown atmosphere. Whenever possible, Self-Contained Breathing Apparatus (SCBA) should be used.
   Skin
IMMEDIATELY flood affected skin with water while removing and isolating all contaminated clothing. Gently wash all affected skin areas thoroughly with soap and water. IMMEDIATELY call a hospital or poison control center even if no symptoms (such as redness or irritation) develop. IMMEDIATELY transport the victim to a hospital for treatment after washing the affected areas.
   Eyes
First check the victim for contact lenses and remove if present. Flush victim's eyes with water or normal saline solution for 20 to 30 minutes while simultaneously calling a hospital or poison control center. Do not put any ointments, oils, or medication in the victim's eyes without specific instructions from a physician. IMMEDIATELY transport the victim after flushing eyes to a hospital even if no symptoms (such as redness or irritation) develop.

Transport.