Tetrandrine

  • 6,6',7,12-Tetramethoxy-2,2'-dimethylberbaman
  • Fanchinine
  • Sinomenine A
  • Tetrandrin
  • (+)-Tetrandrine
  • d-Tetrandrine
Formula
C38H42N2O6
Description
White solid.

Registry Numbers and Inventories.
CAS
518-34-3
R: 20/21/22
RTECS
XE9350000
Merck
12,9369
Beilstein/Gmelin
877811
Beilstein Reference
2-27-00-00889

Properties.
Formula
C38H42N2O6
Formula mass
622.76
Melting point, °C
217
Vapor pressure, mmHg
4.9E-20 (25 C)
Density
1.17 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
6.20 (pKb)
Partition coefficient, pKow
3.55

Hazards and Protection.
Storage
:Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 20 C.
Protection
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self-contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Small spills/leaks
Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...).

Fire.
Fire fighting
Fire fighters should wear positive pressure self-contained breathing apparatus (SCBA) and full turnout gear. Extinguishing agents:
Fire potential
May be combustible at high temperature.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects

First aid
 
   Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
   Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
   Skin
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
   Eyes
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

Transport.