Thebaine

  • Paramorphine
  • 6,7,8,14-Tetradehydro-4,5a-epoxy-3,6-dimethoxy-17-methylmorphinan
Formula
C19H21NO3
Structure
Uses
A naturally occurring constituent of opium that is a precursor of morphine. US DEA Schedule II substance.

Registry Numbers and Inventories.
CAS
115-37-7
EC (EINECS/ELINCS)
204-084-1
26/27/28
22 36/37/39 45
RTECS
QD2975000
RTECS class
Drug
UN (DOT)
1544
Merck
12,9411
Beilstein/Gmelin
48337
Beilstein Reference
4-27-00-02271
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C19H21NO3
Formula mass
311.38
Melting point, °C
195 - 196
Boiling point, °C
468
Vapor pressure, mmHg
6E-9 (25 C)
Density
1.305 g/cm3 (25 C)
Solubility in water
2.2 g/L (25 C)
pKa/pKb
6.77 (pKb)
Heat of vaporization
73.0 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents.
Decomposition
Thermal decomposition may produce carbon monoxide, carbon dioxide, and nitrogen oxides.

Fire.
Flash Point,°C
141
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Fire potential
Non-Combustible
Hazards
Emits toxic fumes under fire conditions.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Very toxic by inhalation, in contact with skin and if swallowed. Target organ(s): Central nervous system. Bowel.
   Ingestion
May be fatal if swallowed.
   Inhalation
May be fatal if inhaled. Material may be irritating to mucous membranes and upper respiratory tract.
   Skin
May cause skin irritation. May be fatal if absorbed through skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician immediately.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
1544
Response guide
Hazard class
3
Packing Group
II