Thioglycol

  • 2-Mercaptoethanol
  • 2-Hydroxy-1-ethanethiol
  • Monothioethyleneglycol
Formula
HSCH2CH2OH
Structure
Description
Colorless liquid with a faint characteristic odor.
Uses
Solvent for dyestuffs, intermediate for producing dyestuffs, pharmaceuticals, rubber chemicals, flotation agents, insecticides, plasticizers, water-soluble reducing agent, biochemical reagent, pvc stabilizers, agricultural chemicals, textile auxiliary.

Registry Numbers and Inventories.
CAS
60-24-2
EC (EINECS/ELINCS)
200-464-6
EC Class
toxic, corrosive, dangerous for the environment
R 20/22 24 34 51/53
S 26 36/37/39 45 61
RTECS
KL5600000
RTECS class
Mutagen; Primary Irritant
UN (DOT)
2966
Merck
13,5894
Beilstein/Gmelin
773648
Beilstein Reference
4-01-00-02428
Swiss Giftliste 1
G-8846
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C2H6OS
Formula mass
78.13
Melting point, °C
-100
Boiling point, °C
157
Vapor pressure, mmHg
1.0 (25 C)
Vapor density (air=1)
2.7
Saturation Concentration
81600 ppm (8.2%) at 20 C
Odor Threshold Odor threshold 0.38 mg/m3
Density
1.1317 g/cm3 (0 C)
Solubility in water
Soluble
Viscosity
3.22 cp (20 C)
Refractive index
1.4963 (20 C)
pKa/pKb
9.74 (pKa)
Partition coefficient, pKow
-0.326
Heat of vaporization
45.9 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
B3 D1A D2B
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not allow contact with water. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Scoop up with a nonsparking tool, then place into a suitable container for disposal. Remove all sources of ignition. Provide ventilation.
Disposal code
6
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizers, calcium hypochlorite, metals, strong acids, caustics, aliphatic amines, isocyanates.
Decomposition
Carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
68
Autoignition, °C
295
Upper exp. limit, %
18
Lower exp. limit, %
2.3
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Combustion generates toxic fumes. Use water spray to keep fire-exposed containers cool. Containers may explode in the heat of a fire. Combustible Liquid. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
2
 
 
Reactivity
1
 

Health.
Exposure limit(s)
OEL-RUSSIA:STEL 1 mg/m3
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause defatting and dermatitis. Repeated or prolonged exposure may cause CNS stimulation.
   Ingestion
Harmful if swallowed. May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May cause muscle paralysis, respiratory failure, and possible death.
   Inhalation
Inhalation of high concentrations may cause central nervous system effects characterized by headache, dizziness, unconsciousness and coma. Causes respiratory tract irritation. May cause dyspnea (difficult breathing from shortness of breath). Exposure to high concentrations of mercaptans can produce unconsciousness with cyanosis, cold extremities and rapid pulse. Mercaptans may cause nausea and headache.
   Skin
May be fatal if absorbed through the skin. Causes irritation with burning pain, itching, and redness.
   Eyes
May cause severe eye irritation. May result in corneal injury.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2966
Response guide
Hazard class
6.1
Packing Group
II
 
HS Code
2930 90 70
 
Std. Transport #
4921890