Thiourea

  • Thiocarbamide
  • 2-Thiourea
  • Pseudothiourea
  • Isothiourea
Formula
H2NCSNH2
Structure
Description
White, lustrous crystals.
Uses
Photographic fixing agent and to remove stains from negatives, manufacture of resins, vulcanization accelerator, a reagent for bismuth, selenite ions.

Registry Numbers and Inventories.
CAS
62-56-6
EC (EINECS/ELINCS)
200-543-5
EC Index Number
612-082-00-0
EC Class
Carcinogenic Category 3; Toxic for reproduction Category 3; Harmful; Dangerous for the Environment
R 22 40 51/53 63
S 36/37 61
RTECS
YU2800000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Drug; Mutagen; Reproductive Effector; Human Data; Primary Irritant
UN (DOT)
2877
Merck
12,9505
Beilstein/Gmelin
605327
Beilstein Reference
4-03-00-00342
RCRA
U219
EPA OPP
600031
Swiss Giftliste 1
G-2097
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
CH4N2S
Formula mass
76.12
Melting point, °C
174 - 177
Vapor pressure, mmHg
0.002 (100 C)
Vapor density (air=1)
2.6
Critical temperature
581
Critical pressure
81.2
Density
1.435 g/cm3 (20 C)
Solubility in water
Soluble
Refractive index
1.637 (30 C)
Partition coefficient, pKow
-1.08
Heat of fusion
15.64 kJ/mol
Heat of vaporization
60.0 kJ/mol
Heat of combustion
-1489 kJ/mol

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Do not breathe dust, vapor, mist, or gas. Do not ingest or inhale. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures. Polymerization may occur upon heating.
Incompatibilities
Oxidizing agents, strong acids, strong bases, acrolein, nitric acid, hydrogen peroxides, acrylaldehyde.
Decomposition
Nitrogen oxides, carbon monoxide, oxides of sulfur, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Autoignition, °C
440
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Water runoff can cause environmental damage. Dike and collect water used to fight fire. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. This material in sufficient quantity and reduced particle size is capable of creating a dust explosion. Extinguishing media: Substance is nonflammable; use agent most appropriate to extinguish surrounding fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Slightly flammable.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
May contain highly toxic fumes of NOx and SOx.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Carcinogin
N-2, CP65
Poison_Class
3
Exposure effects
Chronic ingestion may cause liver damage. May cause cancer according to animal studies. May cause reproductive and fetal effects. Prolonged or repeated exposure may cause thyroid damage. Laboratory experiments have resulted in mutagenic effects.
   Ingestion
Harmful if swallowed. May cause allergic reaction characterized by a rash. May cause severe irritation of the digestive tract. May cause anemia, leukopenia, and thrombocytopenia. May cause bone marrow depression.
   Inhalation
May cause respiratory tract irritation.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause skin eruptions.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting by giving one teaspoon of Syrup of Ipecac. Call a poison control center.
   Inhalation
Remove from exposure to fresh air immediately. If breathing is difficult, give oxygen. Get medical aid. DO NOT use mouth-to-mouth respiration. If breathing has ceased apply artificial respiration using oxygen and a suitable mechanical device such as a bag and a mask.
   Skin
Get medical aid. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
2877
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
THC
 
HS Code
2930 90 70