Thymolphthalein

  • 2',2''-Diisopropyl-5',5''-dimethylphenolphthalein
  • 3,3-Bis(4-hydroxy-3-isopropyl-6-methyl)phthalide
  • 1(3H)-Isobenzofuranone, 3,3-bis[4-hydroxy-2-methyl-5-(1-methylethyl)phenyl]-
Formula
C28H30O4
Structure
Description
White powder or crystals, odorless.
Uses
Used as a pH indicator: colorless 9.3 to blue 10.5.

Registry Numbers and Inventories.
CAS
125-20-2
EC (EINECS/ELINCS)
204-729-7
S 22 24/25
Merck
12,9542
Beilstein/Gmelin
359413
Beilstein Reference
5-18-04-00194
Swiss Giftliste 1
G-8567
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C28H30O4
Formula mass
430.55
Melting point, °C
253
Solubility in water
Insoluble
pKa/pKb
9.90 (pKa)
Partition coefficient, pKow
7.54

Hazards and Protection.
Storage
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Insufficient information
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Avoid ingestion and inhalation. Use with adequate ventilation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
3
Stability
Stable under normal shipping and handling conditions.
Incompatibilities
Strong oxidizers.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dusts at sufficient concentrations can form explosive mixtures with air. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam.
Health
1
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
Inhalation of dust may cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
Dust may cause mechanical irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
HS Code
2932 29 80