Tiopronin

  • N-(2-Mercaptopropionyl)glycine
  • (2-Mercaptopropionamido)acetic acid
  • Thiolpropionamidoacetic acid
Formula
C5H9NO3S
Structure
Uses
Hepatoprotectant against mercury toxicity.

Registry Numbers and Inventories.
CAS
1953-02-2
EC (EINECS/ELINCS)
217-778-4
RTECS
MC0596500
RTECS class
Drug; Reproductive Effector; Human Data
Merck
12,9597
Beilstein/Gmelin
1859822
Beilstein Reference
6-04
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C5H9NO3S
Formula mass
163.2
Melting point, °C
95 - 97
Boiling point, °C
418
Vapor pressure, mmHg
4E-8 (25 C)
Solubility in water
Very soluble
pKa/pKb
3.62 (pKa)
Heat of vaporization
73.7 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Sulfur oxides.

Fire.
Flash Point,°C
207
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful. Harmful if swallowed.
   Ingestion
Harmful if swallowed.
   Inhalation
May be harmful if inhaled.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.