Tolfenamic acid

  • Tolfedine
  • N-(3-Chloro-o-tolyl)anthranilic acid
  • N-(2-Methyl-3-chlorophenyl)anthranilic acid
  • 2-([3-Chloro-2-methylphenyl]amino)benzoic acid
Formula
C14H12ClNO2
Structure
Uses
Non-steroidal anti-inflammatory drug (NSAD).

Registry Numbers and Inventories.
CAS
13710-19-5
EC (EINECS/ELINCS)
237-264-3
20/21/22
RTECS
CB2687500
RTECS class
Drug; Reproductive Effector
Merck
12,9650
Beilstein/Gmelin
657821
Beilstein Reference
6-14
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C14H12ClNO2
Formula mass
261.71
Melting point, °C
211
Boiling point, °C
405
Vapor pressure, mmHg
3E-7 (25 C)
Density
1.45 g/cm3
Solubility in water
Insoluble
pKa/pKb
3.66 (pKa)
Partition coefficient, pKow
5.70
Heat of vaporization
69.3 kJ/mol

Hazards and Protection.
Protection
Wear appropriate government approved respirator, chemical-resistant gloves, safety goggles, other protective clothing.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Flash Point,°C
199
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
Harmful by inhalation, in contact with skin and if swallowed.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If breathing becomes difficult, call a physician.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.