Toluenediamine

  • 2,4-Diaminotoluene
  • Toluene-2,4-diamine
  • 2,4-TDA
  • 4-Methyl-m-phenylenediamine
Formula
4-(CH3)C6H3-1,3-(NH2)2
Structure
Description
Brown crystals. No reported odor.
Uses
Photographic developer, industrial interrmediate.

Registry Numbers and Inventories.
CAS
95-80-7
EC (EINECS/ELINCS)
202-453-1
EC Index Number
612-099-00-3
EC Class
Carcinogenic Category 2; Toxic; Harmful; Irritant; Sensitising; Dangerous for the Environment
R 45 21 25 36 43 51/53
S 53 45 61
RTECS
XS9625000
RTECS class
Agricultural Chemical and Pesticide; Tumorigen; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
1709
Beilstein/Gmelin
2205839
Beilstein Reference
4-13-00-00235
RCRA
U221
Swiss Giftliste 1
G-2957
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H10N2
Formula mass
122.17
Melting point, °C
99
Boiling point, °C
292
Vapor pressure, mmHg
1 (107 C)
Vapor density (air=1)
4.2
Critical temperature
512
Critical pressure
45.4
Density
1.045 g/cm3 (20 C)
Solubility in water
50 g/L (25 C)
Partition coefficient, pKow
0.337

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Disposal code
9
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, acid chlorides, acid anhydrides, chloroformates, strong oxidizing agents.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
169
Autoignition, °C
520
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Use water spray to cool fire-exposed containers. For small fires, use dry chemical, carbon dioxide, or water spray. Cool containers with flooding quantities of water until well after fire is out. For large fires, use water spray, fog or regular foam.
Fire potential
This chemical is combustible.
Combustion products
Highly toxic gases may be generated by thermal decomposition or combustion.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure limit(s)
NIOSH REL: Ca (all isomers) See Appendix A NIOSH IDLH: Potential occupational carcinogen
Carcinogin
I-2B, N-2, CP65
Poison_Class
1*
Exposure effects
Chronic inhalation and ingestion may cause effects similar to those of acute inhalation and ingestion.
   Ingestion
May cause irritation of the digestive tract. May cause methemoglobinemia, cyanosis, convulsions, and death. Methemoglobinemia is characterized by dizziness, drowsiness, headache, breath shortness, cyanosis with bluish skin, rapid heart rate and chocolate-brown colored blood. Ingestion may cause gastritis, vertigo, tremors, convulsions, and possible coma.
   Inhalation
May cause effects similar to those described for ingestion. May cause asthma and shortness of breath.
   Skin
Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. If absorbed, may cause symptoms similar to those for ingestion. May cause a deep staining of the skin. May cause severe dermatitis and urticaria(hives).
   Eyes
Causes eye irritation. May cause blepharitis (inflammation of the eyelids), keratoconjunctivitis and corneal opacity. May cause severe inflammation and edema of the eye and conjunctiva or deeper structures of the eye. May produce lacrimation and permanent blindness.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1709
Response guide
Hazard class
6.1
Packing Group
III
 
USCG CHRIS Code
DAV
 
HS Code
2921 51 19
 
Std. Transport #
4925239