Tosic acid

  • p-Toluenesulfonic acid
  • Toluene-4-sulfonic acid
  • p-Methylphenylsulfonic acid
  • 4-Methylbenzenesulfonic acid
  • Nacure 1040
  • Cyzac 4040
Formula
CH3C6H4SO3H
Structure
Description
Monoclinic leaflets or prisms.
Uses
Used as reagent in kirsten modification of kleber method (for lemon oil).

Registry Numbers and Inventories.
CAS
104-15-4
EC (EINECS/ELINCS)
203-180-0
EC Index Number
016-030-00-2
EC Class
Irritant
RTECS
XT6300000
RTECS class
Other
UN (DOT)
2585
Merck
12,9671
Beilstein/Gmelin
472690
Beilstein Reference
4-11-00-00241
EPA OPP
79058
Swiss Giftliste 1
G-3158
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C7H8O3S
Formula mass
172.2
Melting point, °C
106-107
Boiling point, °C
332
Density
1.24 g/cm3 (20 C)
Solubility in water
Very soluble
Partition coefficient, pKow
0.93
Heat of combustion
-3530 kJ/mol

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
ELIMINATE all ignition sources. Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Stability
Normally stable; unstable at high temperature and pressure.
Incompatibilities
Reacts with water. A strong acid which can react with common metals. Explosions can occur when using an analytical method involving sequential addition if acetic acid, aqueous p-toluenesulfonic acid and acetic anhydride to serum.

Fire.
Flash Point,°C
184
Fire fighting
Small Fires: Dry chemical, carbon dioxide or water spray. Large Fires: Dry chemical, carbon dioxide, alcohol-resistant foam or water spray.
Fire potential
Ignites after considerable preheating.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
1
 

Health.
Exposure limit(s)
OEL-UNITED KINGDOM:TWA 10 ppm (25 mg/m3);STEL 15 ppm (35 mg/m3)
Poison_Class
3
Exposure effects
Abnormal neuropsychologic function has been reported following hydrochloric acid exposure from a leaking tanker truck.
   Ingestion
Ingestion of acids may result in burns, gastrointestinal bleeding, gastritis, perforations, dilation, edema, necrosis, vomiting, stenosis, fistula, and duodenal/jejunal injury.
   Inhalation
Inhalation may produce dyspnea, pleuritic chest pain, upper airway edema, pulmonary edema, hypoxemia, bronchospasm, pneumonitis, and persistent pulmonary function abnormalities. Airway hyperreactivity has also been reported.
   Skin
Contact with molten substance may cause severe burns to skin and eyes. See Inhalation.
   Eyes
See Inhalation.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Do not use mouth-to-mouth method if victim ingested or inhaled the substance; induce artificial respiration with the aid of a pocket mask equipped with a one-way valve or other proper respiratory medical device. Administer oxygen if breathing is difficult.
   Skin
Wash the exposed area with copious amounts of water. A physician should examine the area if irritation or pain persists.
   Eyes
Exposed eyes should be irrigated with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility. Irrigation: in a medical facility, irrigate with sterile saline for at least an hour.

Transport.
UN number
2585
Response guide
Hazard class
8
Packing Group
III
 
USCG CHRIS Code
TAP