Traumatic acid

  • trans-Traumatic acid
  • Dodec-2-enedioic acid
  • (E)-2-Dodecenedioic acid
  • trans-2-Dodecenedioic acid
Formula
HOOC(CH2)8CH=CHCOOH
Structure
Description
White solid.
Uses
A wound healing agent that stimulates cell division near a wound site to form a protective callus.

Registry Numbers and Inventories.
CAS
6402-36-4
EC (EINECS/ELINCS)
229-019-4
Merck
12,9710
Beilstein/Gmelin
1725762
Beilstein Reference
4-02-00-02279
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C12H20O4
Formula mass
228.29
Melting point, °C
162 - 165
Solubility in water
Very soluble
pKa/pKb
4.48 (pKa)

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a dry area. Refrigerator (approx 4 C).
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container.
Disposal code
4
Stability
No data.
Incompatibilities
Bases, oxidizing agents, reducing agents.
Decomposition
Carbon monoxide, carbon dioxide.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Exposure effects
   Ingestion
The toxicological properties of this substance have not been fully investigated.
   Inhalation
May cause respiratory tract irritation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2917 19 90