Tri-p-cresyl phosphate

  • TPC
  • TPCP
  • Tri-p-tolyl phosphate
Formula
C21H21O4P
Structure
Description
Crystalline solid.
Uses
Flame retardant.

Registry Numbers and Inventories.
CAS
78-32-0
EC (EINECS/ELINCS)
201-105-6
EC Index Number
015-016-00-3
EC Class
Harmful; Dangerous for the Environment
Beilstein/Gmelin
1891089
Beilstein Reference
4-06-00-02130
Swiss Giftliste 1
G-3143
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C21H21O4P
Formula mass
368.36
Melting point, °C
77
Boiling point, °C
439
Vapor pressure, mmHg
2E-7 (25 C)
Density
1.247 g/cm3 (20 C)
Solubility in water
Insoluble
Viscosity
7.24 cp (80.35 C)
Surface tension
41 g/s2 (30 C)
Partition coefficient, pKow
5.48
Heat of vaporization
66.9 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Store in a tightly closed container.
Handling
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Protection
Skin: Wear appropriate gloves to prevent skin exposure. Clothing: Wear a chemical apron.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, oxides of phosphorus, carbon dioxide.

Fire.
Flash Point,°C
232
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. To extinguish fire use water spray, dry chemical, carbon dioxide, or chemical foam.

Health.
Poison_Class
4
Exposure effects
A delayed peripheral neuropathy of the dying back or peripheral axonopathy variety predominates. Between 10 and 40 days after exposure, abrupt onset of flaccid paralysis is noted. This may be followed by lower extremity spasticity with clonus, hyperreflexia, hypertonus, and a peculiar spastic gait. In severe cases the full extent of paralysis may not be reached until after 2 to 3 months. Recovery is variable. Mortality is usually low and approximately 5% of victims may remain paralyzed. TOCP produced toxic effects on both male and female REPRODUCTIVE SYSTEMS when Long-Evans rats were given doses of 0 to 400 mg/kg by gavage prior to, and during breeding. Spermatotoxic effects, includes reduced motility, concentration, velocity, and abnormal morphology. Damage to ovarian and uterine tissue also 1999).
   Ingestion
Harmful if swallowed.
   Inhalation
May cause respiratory tract irritation.
   Skin
Harmful if absorbed through the skin.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Wash mouth out with water.
   Inhalation
Remove from exposure to fresh air immediately.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.