Trichothecin

  • 4b-Isocrotonoyloxy-12,13-epoxytrichothec-9-en-8-one
  • Trichothec-9-en-8-one, 12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]-, (4b)-
  • piro[2,5-methano-1-benzoxepin-10,2'-oxirane], trichothec-9-en-8-one deriv.
Formula
C19H24O5
Structure

Registry Numbers and Inventories.
CAS
6379-69-7
26/27/28 36/37/38
36/37/39 45
RTECS
YD0175000
UN (DOT)
2811
Merck
12,9782

Properties.
Formula
C19H24O5
Formula mass
332.4
Melting point, °C
118
Boiling point, °C
451
Vapor pressure, mmHg
2.5E-8 (25 C)
Density
1.24 g/cm3 (20 C)
Solubility in water
0.19 g/L (25 C)
Partition coefficient, pKow
2.09
Heat of vaporization
71.02 kJ/mol

Hazards and Protection.
Storage
Store at 2-8 C.
Protection
Compatible chemical-resistant gloves. Chemical safety goggles. Protective clothing.
Respirators
Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator type N100 (US) or type P3 (EN 143) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator.
Small spills/leaks
Spills should be carefully collected and placed in a bucket. The area should be thoroughly cleaned. The material to be decontaminated should be added to a 5% by volume hypochlorite solution and allowed to stand in a hood for thirty minutes. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Oxides of carbon.

Fire.
Flash Point,°C
234
Fire fighting
Extinguish with water spray, carbon dioxide, dry chemical powder or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
May be fatal if inhaled, swallowed, or absorbed through skin. Causes irritation.
   Inhalation
Material is irritating to mucous membranes and upper respiratory tract.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of contact, immediately wash skin with soap and copious amounts of water. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I