Triethylene glycol dimethacrylate

  • 1,2-bis(2-(methacryloyloxy)ethoxy)ethane
  • Ethylenebis(oxyethylene) methacrylate
  • 2,2'-Ethylenedioxydiethyl dimethacrylate
  • TGM 3
  • TGM 35
  • TGM 3pc
Formula
C14H22O6
Structure
Uses
Crosslinking agent for hard contact lenses.

Registry Numbers and Inventories.
CAS
109-16-0
EC (EINECS/ELINCS)
203-652-6
RTECS
OZ4100000
RTECS class
Mutagen
Beilstein/Gmelin
1797351
Beilstein Reference
4-02-00-01531
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C14H22O6
Formula mass
286.36
Boiling point, °C
135 - 139 (1 torr)
Density
1.0741 g/cm3 (20 C)
Refractive index
1.4623 (20 C)
Partition coefficient, pKow
1.88

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Suitable protective clothing and self-contained resp protective apparatus should be available for use by those who may have to rescue persons overcome by fumes.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Exposure effects
Paresthesia have been reported. Headache, irritability, drowsiness and dizziness may occur. There is no evidence of methyl methacrylate-induced teratogenicity in humans but there are conflicting reports in animals.
   Ingestion
Anorexia and nausea has been reported from inhalational exposure. Stomatitis has resulted from contact. Administration to rats by lavage failed to produce gastric lesions.
   Inhalation
Respiratory depression, pulmonary edema, emphysema, and atelectasis have occurred in animals following large doses.
   Skin
Allergic contact dermatitis has been reported. Eczematous reactions of onychial and paronychial tissues have been reported in patients using acrylic plastic nails. Dystrophic nail changes may persist for months. Irreversible loss of the fingernails has occurred.

First aid
 
   Ingestion
Significant systemic toxicity is not expected after acute ingestion; gastrointestinal decontamination is generally not warranted.
   Inhalation
If symptoms develop, move individual away from exposure and into fresh air. If symptoms persist, seek medical attention. If breathing is difficult, administer oxygen. Keep person warm and quiet; seek immediate medical attention.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.