Triethylene glycol monobutyl ether

  • Triglycol monobutyl ether
  • 2-(2-(2-Butoxyethoxy)ethoxy)ethanol
  • Butoxytriglycol
Formula
C10H22O4
Structure
Description
Liquid. Mild smelling.
Uses
Plasticizer intermediate.

Registry Numbers and Inventories.
CAS
143-22-6
EC (EINECS/ELINCS)
205-592-6
EC Index Number
603-183-00-0
R 36/38
RTECS
KJ9450000
RTECS class
Primary Irritant
Beilstein/Gmelin
1750600
Beilstein Reference
4-01-00-02402
Swiss Giftliste 1
G-6886
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Korea ECL
Listed

Properties.
Formula
C10H22O4
Formula mass
206.32
Melting point, °C
-35.2
Boiling point, °C
278
Vapor pressure, mmHg
0.0005 (25 C)
Vapor density (air=1)
7.1
Density
0.9861 g/cm3 (20 C)
Solubility in water
Miscible
Viscosity
9.36 cp (25 C)
Surface tension
32.6 g/s2 (20 C)
Refractive index
1.44 (19.9 C)
Partition coefficient, pKow
0.08
Heat of vaporization
60.0 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed in a cool place in a tightly closed container.
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed. All five-gallon pails and larger metal containers, including tank cars and tank trucks, should be grounded and/or bonded when material is transferred. Emergency eyewash fountains and safety showers should be available in the immediate vicinity of potential exposure.
Protection
It appears that this material should present no appreciable health hazard from skin contact or from single exposure to vapors generated at room temp.
Respirators
If workplace exposure limit(s) of product or any component is exceeded (see exposure guidelines), a NIOSH/MSHA approved air supplied respirator is advised in absence of proper environmental control. OSHA regulations also permit other NIOSH/MSHA respirators (negative pressure type) under specified conditions.
Small spills/leaks
Small Spill - Absorb liquid on vermiculite, floor absorbent, or other absorbent material and transfer to hood. Large Spill - Eliminate all ignition sources (flares, flames including pilot lights, electrical sparks). Persons not wearing protective equipment should be excluded from area of spill until clean-up has been completed. Stop spill at source.Absorb unrecoverable product. Transfer contaminated absorbent, soil and other materials to containers for disposal.
Stability
Stable.
Incompatibilities
Strong oxidizing agents.
Decomposition
Carbon dioxide and carbon monoxide.

Fire.
Flash Point,°C
144
Fire fighting
Extinguish fire using alcohol foam, water fog, carbon dioxide, dry chemical. Water or foam may cause frothing which can be violent and possibly endanger the life of the firefighter. Wear a self-contained breathing apparatus with a full facepiece operated in the positive pressure demand mode with appropriate turn-out gear and chemical resistant personal protective equipment.
Hazards
Never use welding or cutting torch on or near drum (even empty) because product (even just residue) can ignite explosively.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
-
Exposure effects
Coma has been described after ingestion of 30 to 100 ml of pure glycol ethers in adults.
   Ingestion
Hemorrhagic gastritis was seen in a case of fatal poisoning with methyl ether.
   Inhalation
Ards was reported in one case after ingestion of 500 ml of 9.1% Ethylene glycol butyl ether (egbe).
   Skin
May cause mild skin irritation. Symptoms may include redness and burning of skin.
   Eyes
Eye irritation is generally slight, but may be severe with the propyl ether.

First aid
 
   Ingestion
Emesis is contraindicated due to rapid gi absorption and potential for rapid progression to coma. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Correct severe acidosis (ph < 7.1) With iv nahco3. 1 To 2 meq/kg is a useful starting dose. Monitor abgs. Ethanol (etoh) may inhibit the formation of toxic metabolites, but there are no controlled human studies documenting efficacy. Loading dose - administer 7.6 To 10 ml/kg of 10% etoh in d5w iv over 30 minutes. Maintenance dose - administer 1.39 Ml/kg/hr of 10% etoh in d5w by iv infusion. Aim at achieving and maintaining 100 to 130 mg/dl blood ethanol levels.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
TBE
 
40 Glycol ethers
IMO Chemical Code
18