Triethylene glycol monoethyl ether

  • Ethoxytriglycol
  • Ethoxytriethylene glycol
  • Triglycol monoethyl ether
  • 2-(2-(2-ethoxyethoxy)ethoxy)ethanol
Formula
C8H18O4
Structure
Description
Odorless colorless liquid.
Uses
Solvent (lacquers, paints).

Registry Numbers and Inventories.
CAS
112-50-5
EC (EINECS/ELINCS)
203-978-9
RTECS
KK8950000
RTECS class
Primary Irritant
Beilstein/Gmelin
1700466
Beilstein Reference
4-01-00-02401
Swiss Giftliste 1
G-2970
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C8H18O4
Formula mass
178.26
Melting point, °C
-18.7
Boiling point, °C
256
Vapor pressure, mmHg
0.0024 (25 C)
Vapor density (air=1)
6.38
Odor Threshold Odor threshold Odorless
Critical temperature
415
Critical pressure
26.1
Density
1.027 g/cm3 (20 C)
Solubility in water
Very soluble
Viscosity
7.21 cp (25 C)
Surface tension
34.5 g/s2 (20 C)
Refractive index
1.4379 (19.9 C)
Partition coefficient, pKow
-0.98
Heat of vaporization
51.8 kJ/mol
Heat of combustion
-4597 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed in a cool place in a tightly closed container.
Handling
Containers of this material may be hazardous when emptied. Since emptied containers retain product residues (vapor, liquid, and/or solid), all hazard precautions given in the data sheet must be observed.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Consult your safety representative. neoprene, Wear normal work clothing covering arms and legs.
Respirators
Not required under normal conditions of use.
Small spills/leaks
Small Spill - Collect in a beaker. Large Spill - Eliminate all ignition sources. Persons not wearing protective equipment should be excluded from area of spill until clean-up has been completed. Stop spill at source. Prevent from entering drains, sewers, streams or other bodies of water. Prevent from spreading. If runoff occurs, notify authorities as required. Pump or vacuum transfer spilled product to clean containers for recovery. Absorb unrecoverable product. Transfer contaminated absorbent, soil and other materials to containers for disposal.
Stability
Stable.
Incompatibilities
Flammable and/or toxic gases are generated by combination with with alkali metals, nitrides, and strong reducing agents Reacts with oxoacids and carboxylic acids to form esters plus water.
Decomposition
Sarbon dioxide and carbon monoxide, various hydrocarbons.

Fire.
Flash Point,°C
106
Upper exp. limit, %
6.5
Lower exp. limit, %
1
Fire fighting
Fire Extinguishing Agents Not to Be Used: Water or foam may cause frothing.Fire Extinguishing Agents: Dry chemical, carbon dioxide, or alcohol foam.
Fire potential
Slightly flammable. Combustion requires preheating.
Health
1
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure limit(s)
OSHA PEL: TWA 0.025 ppm (0.25 mg/m3) NIOSH REL: C 0.01 ppm (0.1 mg/m3) NIOSH IDLH: 1 ppm
Poison_Class
-
Exposure effects
Coma has been described after ingestion of 30 to 100 ml of pure glycol ethers in adults.
   Ingestion
Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful.
   Inhalation
See ingestion.
   Skin
May cause mild skin irritation. Symptoms may include redness and burning of skin.
   Eyes
Can cause eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes.

First aid
 
   Ingestion
Emesis is contraindicated due to rapid gi absorption and potential for rapid progression to coma. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Correct severe acidosis (ph < 7.1) With iv nahco3. 1 To 2 meq/kg is a useful starting dose. Monitor abgs. Ethanol (etoh) may inhibit the formation of toxic metabolites, but there are no controlled human studies documenting efficacy. Loading dose - administer 7.6 To 10 ml/kg of 10% etoh in d5w iv over 30 minutes. Maintenance dose - administer 1.39 Ml/kg/hr of 10% etoh in d5w by iv infusion. Aim at achieving and maintaining 100 to 130 mg/dl blood ethanol levels.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
USCG CHRIS Code
TGE
 
40 Glycol ethers
IMO Chemical Code
18
IMO Pollution Category
D