Triethylenetetramine

  • N,N’-bis(Aminoethyl)ethylenediamine
  • TETA
  • 3,6-Diazaoctane-1,8-diamine
  • 1,4,7,10-Tetraazadecane
  • Trientine
Formula
(NH2CH2CH2NHCH2)2
Structure
Description
Viscous, colorless to yellow liquid with an ammonia-like odor. Hygroscopic.
Uses
In detergents, synthesis of dyestuffs, pharmaceuticals.

Registry Numbers and Inventories.
CAS
112-24-3
EC (EINECS/ELINCS)
203-950-6
EC Index Number
612-059-00-5
EC Class
Harmful; Corrosive; Sensitising; Dangerous for the Environment
R 21 34 43 52/53
S 26 36/37/39 45 61
RTECS
YE6650000
RTECS class
Agricultural Chemical and Pesticide; Mutagen; Reproductive Effector; Primary Irritant
UN (DOT)
2259
Merck
12,9796
Beilstein/Gmelin
605448
Beilstein Reference
4-04-00-01242
Swiss Giftliste 1
G-2973
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H18N4
Formula mass
146.24
Melting point, °C
12
Boiling point, °C
267
Vapor pressure, mmHg
0.009 (25 C)
Vapor density (air=1)
5.1
Saturation Concentration
<13 ppm (20 C)
Evaporization number
<0.01 (butyl acetate = 1)
Critical temperature
460
Critical pressure
32
Density
0.9817 g/cm3 (15 C)
Solubility in water
Very soluble
Viscosity
26.7 mPa s (20 C)
Refractive index
1.4986 (20 C)
pKa/pKb
3.93 (pKb)
Partition coefficient, pKow
-1.88
Heat of vaporization
50.5 kJ/mol
Heat of combustion
-4541 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Corrosives area. Do not store in metal containers. Keep containers tightly closed.
D1B D2A D2B E
Handling
Wash thoroughly after handling. Wash hands before eating. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Wash clothing before reuse. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Wear an impervious apron.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Remove all sources of ignition. Provide ventilation. Do not get water inside containers.
Disposal code
5
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Acids, acid chlorides, acid anhydrides, oxidizing agents, chloroformates.
Decomposition
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.

Fire.
Flash Point,°C
129
Autoignition, °C
335
Upper exp. limit, %
7.2
Lower exp. limit, %
0.7
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: Do NOT get water inside containers. For small fires, use dry chemical, carbon dioxide, or water spray. For large fires, use dry chemical, carbon dioxide, alcohol-resistant foam, or water spray. Cool containers with flooding quantities of water until well after fire is out.
Fire potential
May burn but does not ignite readily.
Hazards
When heated, vapors may form explosive mixtures with air: indoors, outdoors, and sewers explosion hazards. May polymerize explosively when heated or involved in a fire. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
1
 
 
Reactivity
0
 

Health.
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause sensitization dermatitis and possible destruction and/or ulceration. Repeated exposure may cause allergic respiratory reaction (asthma).
   Ingestion
May cause severe and permanent damage to the digestive tract. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
   Inhalation
May cause severe irritation of the upper respiratory tract with pain, burns, and inflammation. In rare instances, exposure may cause sensitization, resulting in inflammation of the mucous membranes and in eczematous eruptions.
   Skin
Harmful if absorbed through the skin. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May cause severe irritation and possible burns.
   Eyes
Causes severe eye burns. Low vapor concentrations may cause a temporary visual disturbance known as 'blue haze' or 'halo vision'.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Treat symptomatically and supportively. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. DO NOT use mouth-to-mouth respiration.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Destroy contaminated shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
2259
Response guide
Hazard class
8
Packing Group
II
 
USCG CHRIS Code
TET
 
7 Aliphatic amines
HS Code
2921 29 00
 
Std. Transport #
4931468
 
IMO Chemical Code
17
IMO Pollution Category
D
IMO Hazard code
S