Trifluoroacetic acid anhydride

  • Trifluoroacetyl anhydride
  • Trifluoroacetic anhydride
  • Perfluoroacetic anhydride
  • Acetic acid, trifluoro-, anhydride
  • 2,2,2-Trifluoroacetic anhydride
  • Hexafluoroacetic anhydride
Formula
(CF3CO)2O
Structure
Description
Clear, colorless liquid with a pungent odor.

Registry Numbers and Inventories.
CAS
407-25-0
EC (EINECS/ELINCS)
206-982-9
EC Class
harmful, corrosive, dangerous for the environment
R 14 20 25 35
S 23 26 36/37/39 45
RTECS
AJ9800000
RTECS class
Primary Irritant
UN (DOT)
2922
Beilstein/Gmelin
746197
Beilstein Reference
4-02-00-00469
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C4F6O3
Formula mass
210.04
Melting point, °C
-65
Boiling point, °C
39.4
Vapor pressure, mmHg
439 (25 C)
Density
1.487 g/cm3 (20 C)
Solubility in water
Insoluble
Refractive index
1.2735 (20 C)
Partition coefficient, pKow
2.56
Heat of vaporization
28.4 kJ/mol

Hazards and Protection.
Storage
Store in a cool, dry place. Corrosives area. Keep containers tightly closed.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Do not get in eyes, on skin, or on clothing. Do not ingest or inhale. Discard contaminated shoes.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Clean up spills immediately, using the appropriate protective equipment.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidizing agents, strong acids, strong bases, alcohols, water.
Decomposition
Carbon monoxide, carbon dioxide, hydrogen fluoride.

Fire.
Flash Point,°C
-26
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing media: For small fires, use water spray, dry chemical, carbon dioxide or chemical foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Contact with metals may evolve flammable hydrogen gas.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
   Ingestion
May cause hemorrhaging of the digestive tract. May cause corrosion and permanent tissue destruction of the esophagus and digestive tract.
   Inhalation
May cause ulceration and perforation of the nasal septum if inhaled in excessive quantities. May cause burns to the respiratory tract. Inhalation may be fatal as a result of spasm, inflammation, edema of the larynx and bronchi, chemical pneumonitis and pulmonary edema.
   Skin
Causes skin burns. May cause deep, penetrating ulcers of the skin.
   Eyes
Causes severe eye burns. Contact may cause ulceration of the conjunctiva and cornea.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Do NOT allow victim to rub or keep eyes closed.

Transport.
UN number
2922
Response guide
Hazard class
8
Packing Group
I; II; III
 
HS Code
2915 90 80