Trimethylamine

  • N,N-Dimethylmethanamine
  • N,N-Dimethylmethamine
Formula
(CH3)3N
Structure
Description
A colorless solution with a fishlike odor at low concentrations changing to ammonia-like odor at higher concentrations.
Uses
Organic synthesis, especially of choline salts, warning agent for natural gas, manufacture of disinfectants, flotation agent, insect attractant, quaternary ammonium compounds, plastics.

Registry Numbers and Inventories.
CAS
75-50-3
EC (EINECS/ELINCS)
200-875-0
EC Index Number
612-001-01-6
EC Class
Extremely flammable; Harmful; Corrosive
RTECS
PA0350000
RTECS class
Reproductive Effector
UN (DOT)
1083
Merck
12,9841
Beilstein/Gmelin
956566
Beilstein Reference
4-04-00-00134
Swiss Giftliste 1
G-3008
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C3H9N
Formula mass
59.11
Melting point, °C
-117.1
Boiling point, °C
2.87
Vapor pressure, mmHg
681 (0 C)
Vapor density (air=1)
2
Odor Threshold Odor threshold 0.21 ppb
Critical temperature
160.1
Critical pressure
40.2
Density
0.6709 g/cm3 (0 C)
Solubility in water
480 g/L
Viscosity
0.321 cp (25 C)
Surface tension
13.47 g/s2 (25 C)
pKa/pKb
4.20 (pKb)
Partition coefficient, pKow
0.16
Heat of fusion
6.5 kJ/mol
Heat of vaporization
23.0 kJ/mol
Heat of combustion
-2440 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Refrigerator/flammables.
Handling
Wash thoroughly after handling. Use with adequate ventilation. Ground and bond containers when transferring material. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Do not ingest or inhale. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Remove all sources of ignition.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
May react with acids, oxidizing materials, chlorine, hypochlorite, halogenated compounds, reactive organic compounds and some metals, and mercury and nitrosating compounds. Self-reactive. Potentially explosive reaction with bbromine + heat, ethylene oxide, triethynyl-aluminum.
Decomposition
Nitrogen oxides, carbon monoxide, carbon dioxide, hydrocarbons, amines.

Fire.
Flash Point,°C
-7
Autoignition, °C
190
Upper exp. limit, %
11.6
Lower exp. limit, %
2
Fire fighting
Do not extinguish fire unless flow can be stopped. Use water in flooding quantities as fog. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Fire potential
FLAMMABLE.
Hazards
Flashback along vapor trail may occur. Vapor may explode if ignited in an enclosed area. Vapor is heavier than air and may travel a considerable distance to a source of ignition and flash back.
Combustion products
Fire will produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
4
 
 
Reactivity
0
 

Health.
Exposure limit(s)
TLV (as TWA): 5 ppm; 12 mg/m3 ; as STEL: 15 ppm; 36 mg/m3 (ACGIH 1997). NIOSH REL: TWA 10 ppm (24 mg/m3) ST 15 ppm (36 mg/m3)
Poison_Class
3
Exposure effects
Prolonged or repeated skin contact may cause dermatitis.
   Ingestion
Harmful if swallowed. May cause severe gastrointestinal tract irritation with nausea, vomiting and possible burns.
   Inhalation
May cause severe irritation of the respiratory tract with sore throat, coughing, shortness of breath and delayed lung edema.
   Skin
May cause severe irritation and possible burns.
   Eyes
Contact with eyes may cause severe irritation, and possible eye burns. Contact may cause ulceration of the conjunctiva and cornea.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
1083
Response guide
Hazard class
2.1
USCG CHRIS Code
TMA
 
7 Aliphatic amines
Std. Transport #
4907880
 
IMO Chemical Code
17
IMO Pollution Category
(C)
IMO Hazard code
(S/P)