Trimethylpyruvic acid

  • tert-Butylglyoxlic acid
  • 3,3-Dimethyl-2-oxobutanoic acid
  • Trimethylpyroracemic acid
  • Trimethylpyroracemic acid
Formula
C6H10O3
Structure

Registry Numbers and Inventories.
CAS
815-17-8
EC (EINECS/ELINCS)
212-418-2
Beilstein/Gmelin
636025
Beilstein Reference
4-03-00-01595
Canada DSL/NDSL
NDSL
US TSCA
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C6H10O3
Formula mass
130.14
Melting point, °C
90
Boiling point, °C
189
Vapor pressure, mmHg
0.37 (25 C)
Solubility in water
Very soluble
Refractive index
1.4222 (25 C)
pKa/pKb
2.65 (pKa)
Heat of vaporization
46.2 kJ/mol

Hazards and Protection.

Fire.
Flash Point,°C
78

Health.
Exposure effects
   Ingestion
Significant esophageal or gastrointestinal tract irritation or burns may occur following ingestion.
   Inhalation
Causes irritation. Effect may be delayed for up to 24 - 72 hours.
   Skin
Causes irritation. Effect may be delayed for up to 24 - 72 hours.
   Eyes
Causes irritation. Effect may be delayed for up to 24 - 72 hours.

First aid
 
   Ingestion
Consider gastric lavage after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Protect airway by placement in Trendelenburg and left lateral decubitus position or by endotracheal intubation. Control any seizures first. Use of activated charcoal or dilution with milk or water should also be considered.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with inhaled beta2 agonist and oral or parenteral corticosteroids. Respiratory tract irritation, if severe, can progress to pulmonary edema which may be delayed in onset up to 24 to 72 hours after exposure in some cases.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician may need to examine the area if irritation or pain persists.
   Eyes
Irrigate exposed eyes with copious amounts of room temperature water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.