Triphenylarsine oxide

  • Arsine oxide, triphenyl-
Formula
C18H15AsO
Structure
Description
White powder powder.
Uses
Antimicrobial.

Registry Numbers and Inventories.
CAS
1153-05-5
EC (EINECS/ELINCS)
214-571-0
R 23/25 50/53
S 20/21 28 45 60 61
UN (DOT)
3280
Beilstein/Gmelin
2939833
Beilstein Reference
4-16-00-01176
Canada DSL/NDSL
DSL
US TSCA
Listed

Properties.
Formula
C18H15AsO
Formula mass
322.23
Melting point, °C
198
Density
1.45 g/cm3

Hazards and Protection.
Storage
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, arsine, arsenic fumes, arsenic oxides.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Chronic exposure to arsenical dust may cause breath shortness, nausea, chest pains, and garlic odor. Inorganic arsenic compounds may cause skin and lung cancers in humans.
   Ingestion
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Ingestion of arsenical compounds may cause burning of the lips, throat constriction, swallowing difficulties, severe abdominal pain, severe nausea, projectile vomiting, and profuse diarrhea. Ingestion of arsenic compounds can produce convulsions, coma, and possibly death within 24 hours.
   Inhalation
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. May cause respiratory muscle paralysis. Other symptoms include lethargy, irritation, sore throat, nose bleeds, hoarseness, cough, chest tightness, difficulty breathing, nausea, vomiting, dizziness, fever, Inhalation of arsenic compounds may lead to irritation of the respiratory tract and leading to possible nasal perforation. Long-term exposure to arsenic compounds may produce impairment of peripheral circulation.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
3280
Response guide