Tropicamide

  • Bistropamide
  • Epitromina
  • N-Ethyl-alpha-(hydroxymethyl)-N-(4-pyridinylmethyl)benzeneacetamide
  • N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamine
  • Mydriacyl
  • Mydriat
Formula
C17H20N2O2
Structure
Description
White powder.
Uses
Acetylcholine receptor antagonist.

Registry Numbers and Inventories.
CAS
1508-75-4
EC (EINECS/ELINCS)
216-140-2
20/21/22 36/37/38 42/43
22 26 36
RTECS
CY1487860
RTECS class
Drug
Merck
12,9911
Beilstein/Gmelin
285563
Beilstein Reference
5-22-09-00359
Canada DSL/NDSL
DSL
Japan ENCS (MITI)
Listed

Properties.
Formula
C17H20N2O2
Formula mass
284.36
Boiling point, °C
493
Vapor pressure, mmHg
2E-10 (25 C)
Solubility in water
Insoluble
pKa/pKb
8.51 (pKb)
Heat of vaporization
80.0 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed. Store at 2-8 C
Protection
Compatible chemical-resistant gloves. Chemical safety goggles.
Respirators
Government approved respirator.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides.

Fire.
Flash Point,°C
252
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. May cause sensitization by inhalation and skin contact. Target organ(s): Nerves.
   Ingestion
Harmful if swallowed.
   Inhalation
Harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
   Skin
Causes skin irritation. Harmful if absorbed through skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.