trans-2,3-Dimethyloxirane

  • trans-2-Butylene oxide
  • trans-2-Butene oxide
  • trans-2,3-Butylene oxide
  • trans-2,3-Epoxybutane
  • trans-2,3-Butene oxide
Formula
C4H8O
Structure
Description
Colorless liquid. Aromatic odor.

Registry Numbers and Inventories.
CAS
21490-63-1
EC (EINECS/ELINCS)
244-406-8
R 11 20/21/22 36/37/38 40
S 16 23 26 36/37/39
RTECS
EK3855040
RTECS class
Mutagen
UN (DOT)
1993
Beilstein/Gmelin
79772
Beilstein Reference
5-17-01-00061

Properties.
Formula
C4H8O
Formula mass
72.10
Melting point, °C
-82.6
Boiling point, °C
54
Vapor pressure, mmHg
300 (25 C)
Vapor density (air=1)
2.48
Critical temperature
217
Critical pressure
35.32
Density
0.81 g/cm3 (15 C)
Solubility in water
Soluble
Refractive index
1.3713 (20 C)
Partition coefficient, pKow
0.80
Heat of vaporization
28.1 kJ/mol

Hazards and Protection.
Storage
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Store in a cool, dry, well-ventilated area away from incompatible substances. Flammables-area. Store protected from moisture.
Handling
Wash thoroughly after handling. Ground and bond containers when transferring material. Use spark-proof tools and explosion proof equipment. Avoid contact with eyes, skin, and clothing. Empty containers retain product residue, (liquid and/or vapor), and can be dangerous. Keep container tightly closed. Avoid contact with heat, sparks and flame. Avoid ingestion and inhalation. Use with adequate ventilation. Do not allow contact with water. Wash clothing before reuse. Do not pressurize, cut, weld, braze, solder, drill, grind, or expose empty containers to heat, sparks or open flames. Keep from contact with moist air and steam.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Absorb spill with inert material, (e.g., dry sand or earth), then place into a chemical waste container. Avoid runoff into storm sewers and ditches which lead to waterways. Clean up spills immediately, using the appropriate protective equipment. Remove all sources of ignition. Use a spark-proof tool. Provide ventilation. Do not get water inside containers. A vapor suppressing foam may be used to reduce vapors.
Stability
Stable at room temperature in closed containers under normal storage and handling conditions.
Incompatibilities
Moisture, strong oxidizing agents, strong acids, strong bases.
Decomposition
Carbon monoxide, irritating and toxic fumes and gases, carbon dioxide.

Fire.
Flash Point,°C
-27
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Will burn if involved in a fire. Use water spray to keep fire-exposed containers cool. Water may be ineffective. Material is lighter than water and a fire may be spread by the use of water. Containers may explode in the heat of a fire. Will be easily ignited by heat, sparks or flame. Extinguishing media: For small fires, use dry chemical, carbon dioxide, water spray or alcohol-resistant foam. For large fires, use water spray, fog, or alcohol-resistant foam. Use water spray to cool fire-exposed containers. Water may be ineffective.
Health
2
 
Flammability
3
 
 
Reactivity
0
 

Health.
Exposure effects
Effects may be delayed.
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea. The toxicological properties of this substance have not been fully investigated. Ingestion of large amounts may cause CNS depression.
   Inhalation
Causes respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Aspiration may lead to pulmonary edema. Vapors may cause dizziness or suffocation. Can produce delayed pulmonary edema. May cause burning sensation in the chest.
   Skin
Causes skin irritation. May cause irritation and dermatitis. May cause cyanosis of the extremities.
   Eyes
Causes eye irritation. May cause chemical conjunctivitis and corneal damage.

First aid
 
   Ingestion
Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
   Skin
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
UN number
1993
Response guide