Vanadic acid, ammonium salt
- Ammonium vanadate
- Ammonium vanadium oxide
Mandelin's reagent (0.5 G ammonium vanadate in 54 ml h2so4) is used as a spray color revealing device in analytical toxicology of drugs.
Registry Numbers and Inventories.
2.304 g/cm3 (25 C)
Solubility in water
Hazards and Protection.
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Wear appropriate personal protective clothing to prevent skin contact. Wear appropriate eye protection to prevent eye contact.
Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive pressure-mode. <BR>Escape from suddenly occurring respiratory hazards: Respirators for escape purposes only: any air-purifying, full-facepiece respirator with a high-efficiency particulate filter. Any appropriate escape-type, self-contained breathing apparatus.
Do not touch damaged containers or spilled material unless wearing appropriate protective clothing. Stop leak if you can do it without risk. Cover with plastic sheet to prevent spreading. Absorb or cover with dry earth, sand or other non-combustible material and transfer to containers. DO NOT GET WATER INSIDE CONTAINERS.
Lithium, chlorine trifluoride vanadium dust, vanadium fume)
Use method most appropriate to fight surrounding fire.
Fire may produce irritating, corrosive and/or toxic gases.
IDHL: 35 mg/m3
CNS depression may occur, usually with fatal doses. Sensorimotor hemiparesis and aphasia developed shortly after ingestion of ammonium metavanadate. CNS manifestations include tremors, headaches, tinnitus, and changes in mental status.
Abdominal cramping, diarrhea, black stools, and green tongue developed in volunteers given ammonium vanadyl tartrate.
Pulmonary irritation leading to pulmonary edema is a possible effect with high concentrations. Occupational asthma has been reported.
Dermatitis, and green discoloration of the skin, may be seen with exposure to vanadium compounds.
Administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Chelation - the level at which chelation is necessary is uncertain, especially since systemic symptoms have been rare even in the presence of an excessive body burden. Two chelators have been investigated for vanadium; edta and bal.
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.
I; II; III