Viscous, pale yellow oil.
calcium channel blocker
Registry Numbers and Inventories.
Drug; Reproductive Effector; Human Data
Boiling point, °C
232 - 235 (0.01 torr)
Solubility in water
1.5448 (25 C)
Hazards and Protection.
Store in a cool, dry location in a tightly closed container.
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Latex gloves, chemical safety goggles and disposable protective clothing.
A NIOSH approved respirator should be available.
While wearing recommended personal protective equipment, absorb liquid with paper and place in a container for disposal.
Stable at normal temperatures and pressures.
Wear self contained breathing apparatus and protective clothing. Use water spray, carbon dioxide, dry chemical or foam to extinguish fire.
May emit toxic fumes.
CNS depression, secondary to hemodynamic instability occurs following significant overdose. Effects may include drowsiness, confusion, and coma. Cerebral infarction has been reported.
Nausea and vomiting occur frequently. Ileus can also occur. Concretions from sustained-release dosage forms have been found at autopsy. Bowel infarction has also been reported.
Respiratory effects are uncommon but noncardiogenic pulmonary edema, may occur following significant overdose.
Causes irritation. Flushing is common with nifedipine.
Flush mouth with water. See medical assistance.
Remove to fresh air.
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes.
Flush with water and seek medical assistance.