Vernolate

  • Perbulate
  • Propyl-N,N-dipropylthiolcarbamate
  • S-Propyl dipropylcarbamothioate
  • S-Propyldipropylthiocarbamate
  • Propyl dipropylthiolcarbamate
  • Veratridine
Formula
C10H21NOS
Structure
Description
Clear liquid. Faint aromatic odor.
Uses
Selective soil incorporated herbicide.

Registry Numbers and Inventories.
CAS
1929-77-7
EC (EINECS/ELINCS)
217-681-7
EC Index Number
006-066-00-7
EC Class
Harmful; Dangerous for the Environment
RTECS
FA4725000
RTECS class
Agricultural Chemical and Pesticide; Mutagen
Merck
12,10097
Beilstein/Gmelin
1767659
Beilstein Reference
4-04-00-00487
RCRA
U385
EPA OPP
41404
Swiss Giftliste 1
G-6625
Austrailia AICS
Listed

Properties.
Formula
C10H21NOS
Formula mass
203.35
Boiling point, °C
140
Vapor pressure, mmHg
0.01
Density
0.944 g/cm3 (30 C)
Solubility in water
107 mg/L at 25 C
Refractive index
1.4736 (23 C)

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Absorb on vermiculite or similar material. Sweep up and place in an approved container. Hod for disposal. Wash contaminated surfaces to remove any residuals.
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Flash Point,°C
121
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
4
Exposure effects
Exposure to thiram or mbdt-carb (based on animal studies) may cause weakness, ataxia, ascending paralysis and hypothermia. Peripheral neuropathy (pain, numbness and weakness of the extremities) has been noted following exposure to thiuram (the ethyl analog of thiram). No adverse reproductive effects (testicular parameters) in male mice were observed following methyl thiophanate doses up to 1000 mg/kg orally for 5 consecutive days (Traina et al, 1998). Maternal toxicity was evident in female rats.
   Ingestion
Nausea, vomiting and diarrhea may occur.
   Inhalation
Respiratory failure, requiring ventilatory support, has been reported following ingestions.
   Skin
Exposure to dusts, sprays, solutions, wettable powder suspensions or emulsions of these agents may lead to skin and mucous membrane irritation.
   Eyes
May cause irritation.

First aid
 
   Ingestion
Ipecac induced vomiting is not recommended because of the potential for cns depression and seizures. Consider after ingestion of a potentially life-threatening amount of poison if it can be performed soon after ingestion (generally within 1 hour). Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents. Intravenous fluids may be useful in restoring extracellular fluid volume following severe vomiting and diarrhea. Oxygen therapy is effective in relieving the distress of antabuse-like reactions rarely associated with exposure to thiram and possibly the mbdt-carb compounds. No specific antidotes are available for poisoning by these compounds. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Get immediate medical attention.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists.
   Eyes
If symptoms develop, immediately move individual away from exposure and into fresh air. Flush eyes gently with water for at least 15 minutes while holding eyelids apart; seek immediate medical attention.

Transport.