Vitamin D2

  • Calciferol
  • (3-beta,5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol
  • Ergocalciferol
  • 4-methylene-3-{2-[7a-methyl-1-(1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-ylidene]-ethylidene}-cyclohexanol
Formula
C28H44O
Structure
Description
Odorless white crystals.
Uses
Medication, rodenticide.

Registry Numbers and Inventories.
CAS
50-14-6
EC (EINECS/ELINCS)
200-014-9
EC Index Number
603-179-00-9
S 22 36/37 45
RTECS
KE1050000
RTECS class
Agricultural Chemical and Pesticide; Drug; Reproductive Effector; Human Data
UN (DOT)
2811
Merck
12,10156
Beilstein/Gmelin
1916682
Beilstein Reference
4-06-00-04404
EPA OPP
202900
Swiss Giftliste 1
G-7920
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C28H44O
Formula mass
396.66
Melting point, °C
115-118
Solubility in water
Insoluble

Hazards and Protection.
Storage
Store in a cool, dry, well-ventilated area away from incompatible substances. Poison room locked/refrigerator. Keep containers tightly closed. Store protected from light and air. Store under nitrogen.
Handling
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use only in a well ventilated area. Do not get in eyes, on skin, or on clothing. Keep container tightly closed. Do not ingest or inhale. Store protected from light. Store protected from air. Use only in a chemical fume hood.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant a respirator's use.
Small spills/leaks
Wash area with soap and water. Clean up spills immediately, using the appropriate protective equipment. Sweep up, then place into a suitable container for disposal. Avoid generating dusty conditions. Provide ventilation.
Stability
Stable under normal temperatures and pressures. Decomposes on exposure to air and light.
Incompatibilities
Strong oxidizing agents, strong acids, strong bases, air, direct light.
Decomposition
Carbon monoxide, carbon dioxide, acrid smoke and fumes.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire. In case of fire use water spray, dry chemical, carbon dioxide, or appropriate foam.
Fire potential
Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes.
Hazards
Shows signs of decomposition when stored for a few days at room temperature.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.
Health
3
 
Flammability
0
 
 
Reactivity
0
 

Health.
Poison_Class
2
Exposure effects
Chronic exposure may cause reproductive disorders and teratogenic effects. Vitamin D ingested in excess results in hypercalcemia, which is caused by excessive absorption of massive quantities of calcium by the intes tine and enhanced bone resorption. Causes impairment of kidneys inclu ding excessive thirst and urination, nocturia, proteinuria, and decrea sed urinary concentration ability.
   Ingestion
May be fatal if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause weight loss and irritability. Symptoms include weakness, fatigue, lassitude, and headache. Mental dullness and coma may develop. Impairs kidney function, including excessive thirst and urination. Causes calcification in cornea and conjunctiva in form of band keratopathy. Mimics hyperparathyroidism with muscular weakness, nervousness, itching, and hypertension.
   Inhalation
May cause effects similar to those described for ingestion. Causes irritation of the mucous membrane and upper respiratory tract.
   Skin
May cause skin irritation.
   Eyes
May cause eye irritation.

First aid
 
   Ingestion
If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Induce vomiting only when instructed to do so by a physician.
   Inhalation
Get medical aid immediately. Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
   Skin
Get medical aid immediately. Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Discard contaminated clothing in a manner which limits further exposure. Destroy contaminated shoes.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately.

Transport.
UN number
2811
Response guide
Hazard class
6.1
Packing Group
I; II; III
 
USCG CHRIS Code
EGF