Vitamin K5

  • 4-Amino-2-methyl-1-naphthalenol
  • 4-Amino-2-methyl-1-naphthol
  • 1-Hydroxy-2-methyl-4-aminonaphthalene
  • Kayvisyn
  • 2-Methyl-4-amino-1-hydroxynaphthalene
  • 2-Methyl-4-amino-1-naphthol
Formula
C11H11NO
Structure
Description
Light pink powder.
Uses
Chemical probe to study insulin-activated hexose transport.

Registry Numbers and Inventories.
CAS
83-70-5
R:36/37/38
S:22 36/37/39
RTECS
QL3350000
Merck
12,10162
Beilstein/Gmelin
2719282
Beilstein Reference
3-13-00-01920

Properties.
Formula
C11H11NO
Formula mass
173.21
Melting point, °C
150 - 152
Boiling point, °C
385.1
Vapor pressure, mmHg
1.75E-6
Critical temperature
585
Critical pressure
42.6
Density
1.232 g/cm3 (20 C)
Solubility in water
Slightly soluble
pKa/pKb
9.78 (pKa)
Partition coefficient, pKow
2.33
Heat of vaporization
65.87 kJ/mol

Hazards and Protection.
Storage
Store at 20 C away from incompatible substances.
Protection
Wear appropriate personal protective equipment and clothing including lab coat, safety goggles, gloves and NIOSH-approved respirator.Avoid contact of material with skin or eyes. Mechanical ventilation or local exhaust as needed to control exposure to dust, vapors or mists. Access to a safety shower and eye-wash.
Respirators
A qualified industrial hygienist should evaluate the need for respiratory protection. Use respiratory protection approved by NIOSH (or equivalent) and appropriate to the hazard.
Small spills/leaks
Collect in a manner that does not create dust and place in a suitable waste container. Avoid contact of material with skin or eyes. Use adequate ventilation.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Incompatible with strong oxidizing agents
Decomposition
Hazardous decomposition products may include carbon and nitrogen oxides and/or Hydrogen Chloride fumes and vapors. Hazardous polymerization will not occur.

Fire.
Flash Point,°C
186.7
Fire fighting
Use media suitable to extinguish the supporting or surrounding fire. Wear NIOSH (or equivalent) approved self contained breathing apparatus. For small fires only: use carbon dioxide, dry powder or foam.
Hazards
Emits toxic fumes under fire conditions.

Health.
Exposure effects
   Ingestion
Chronic ingestion or excessive dosage may cause irritation to the mouth, throat and gastrointestinal tract. Ingestion of large amounts may cause ataxia, urine discoloration and peripheral sensory neuropathy.
   Inhalation
May cause irritation to mucous membranes and upper respiratory tract.
   Skin
Contact may cause flushing, irritation and/or allergic reaction. Reddening, itching and inflammation may result.
   Eyes
Contact may cause irritation with redness, tearing and blurred vision.

First aid
 
   Ingestion
Drink water and seek immediate medical attention. Avoid alcoholic beverages. Never give anything by mouth to an unconscious person.
   Inhalation
Remove the victim from exposure and move to fresh air. If breathing is difficult, give oxygen. If not breathing, give artificial respiration. Keep victim quiet and warm. Seek immediate medical attention.
   Skin
Flush with water, then wash thoroughly with soap and water. Remove contaminated clothing and wash before reuse. Seek medical attention if irritation persists.
   Eyes
Flush with water for 15 minutes. Seek medical advice if irritation persists.

Transport.