Withaferin A

  • NSC-101088
  • 5-beta-Ergosta-2,24-dien-26-oic acid, 5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-oxo-, delta-lactone, (20S,22R)
  • Withaferine A
Formula
C28H38O6
Description
White solid.

Registry Numbers and Inventories.
CAS
5119-48-2
S: 22 36/37
RTECS
KE7288500
Merck
12,10184
Beilstein/Gmelin
1335150
Beilstein Reference
5-19-06-00604

Properties.
Formula
C28H38O6
Formula mass
470.61
Melting point, °C
252-253
Vapor pressure, mmHg
1.9E-21 925 C)
Density
1.28 g/cm3 (20 C)
Solubility in water
Insoluble
pKa/pKb
13.26 (pKa)
Partition coefficient, pKow
3.80

Hazards and Protection.
Storage
Keep container tightly closed. Keep container in a cool, well-ventilated area. Do not store above 4 C.
Protection
Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Small spills/leaks
Use appropriate tools to put the spilled solid in a convenient waste disposal container.
Stability
Stable at normal temperatures and pressures.

Fire.
Fire fighting
Use dry chemical powder, water spray, fog or foam. Do not use water jet. Wear positive pressure SCBA and full turnout gear.
Fire potential
May be combustible at high temperature.
Health
0
 
Flammability
1
 
 
Reactivity
0
 

Health.
Exposure effects
Possible cancer hazard. Contains material that may cause cancer or heritable genetic effects based on animal data.

First aid
 
   Ingestion
Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately. Loosen tight clothing such as a collar, tie, belt or waistband.
   Inhalation
If inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
   Skin
In case of contact, immediately flush skin with plenty of water. Remove contaminated clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before reuse. Get medical attention.
   Eyes
Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.

Transport.