Xanthuric acid

  • Xanthurenic acid
  • 8-Hydroxykynurenic acid
  • 4,8-Dihydroxyquinaldic acid
  • 4,8-Dihydroxyquinaldinic acid
  • 2-Quinolinecarboxylic acid, 4,8-dihydroxy
  • 4,8-Dihydroxyquinoline-2-carboxylic acid
Formula
C10H7NO4
Structure
Description
Yellow crystalline powder.
Uses
A tryptophan metabolite.

Registry Numbers and Inventories.
CAS
59-00-7
EC (EINECS/ELINCS)
200-410-1
R 36/37/38
RTECS
UZ9275000
RTECS class
Tumorigen
Merck
12,10202
Beilstein/Gmelin
185954
Beilstein Reference
4-22-00-02513
New Zealand
Listed

Properties.
Formula
C10H7NO4
Formula mass
205.17
Melting point, °C
297
Solubility in water
Very soluble
pKa/pKb
1.2- (pKa)

Hazards and Protection.
Storage
Store in a cool, dry place. Keep container closed when not in use.
Handling
Wash thoroughly after handling. Wash hands before eating. Use with adequate ventilation. Do not get on skin or in eyes. Avoid ingestion and inhalation.
Protection
Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure.
Respirators
Follow the OSHA respirator regulations found in 29CFR 1910.134 or European Standard EN 149. Always use a NIOSH or European Standard EN 149 approved respirator when necessary.
Small spills/leaks
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, using the appropriate protective equipment.
Disposal code
4
Stability
Stable under normal temperatures and pressures.
Incompatibilities
Strong oxidants.
Decomposition
Irritating and toxic fumes and gases.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing media: Use agent most appropriate to extinguish fire.

Health.
Exposure effects
   Ingestion
May cause gastrointestinal irritation with nausea, vomiting and diarrhea.
   Inhalation
Causes respiratory tract irritation.
   Skin
Causes skin irritation.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
Do NOT induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid.
   Inhalation
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid if cough or other symptoms appear.
   Skin
Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists.
   Eyes
Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.

Transport.
HS Code
2933 49 90