Zephiramine

  • Tetradecylbenzyldimethylammonium chloride
  • Barquat ms 100
  • Benzyldimethylmyristylammonium chloride
  • Benzyldimethyltetradecylammonium chloride
  • n-Benzyl-n-Tetradecyldimethylammonium chloride
Formula
C6H5CH2N+(CH3)2C14H29Cl-
Structure
Description
Free-flowing powder.
Uses
Surfactant and detergent.

Registry Numbers and Inventories.
CAS
139-08-2
EC (EINECS/ELINCS)
205-352-0
EC Class
harmful, irritant
R 22 36/38
RTECS
BO7150000
RTECS class
Primary Irritant
Beilstein/Gmelin
4062599
EPA OPP
69184
Swiss Giftliste 1
G-4539
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed
Japan ENCS (MITI)
Listed
Korea ECL
Listed

Properties.
Formula
C23H42ClN . 2H2O
Formula mass
368.05
Melting point, °C
49 - 52
Solubility in water
> 1 g/L
Partition coefficient, pKow
1.81

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Chemical splash goggles in compliance with OSHA regulations are advised; however, OSHA regulations also permit other type safety glasses. Whre chemical resistant gloves. To prevent repeated or prolonged skin contact, wear impervious clothing and boots.
Respirators
Use NIOSH/MSHA approved respirator appropriate for exposure of concern.
Small spills/leaks
Evacuate area and ventilate. Wear protective equipment. If required, use an inert absrobent. Sweep up and place in an appropriate container for disposal. Wash contaminated surfaces.
Disposal code
3
Stability
No data.
Incompatibilities
Strong oxidizing agents.

Fire.
Fire fighting
Wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Use agent most appropriate to extinguish fire.

Health.
Poison_Class
3
Exposure effects
CNS depression progressing to coma, seizures, shock, and respiratory muscle paralysis has been reported.
   Ingestion
Vomiting, diarrhea and abdominal pain may occur. Ingestion of concentrated solutions may produce burns of the mouth, pharynx, and esophagus. Hemorrhagic gi tract necrosis and peritonitis have been reported.
   Inhalation
Respiratory muscle paralysis, pulmonary edema, occupational asthma, and hypoxemia have been reported.
   Skin
Dermal necrosis has resulted from exposure to cetrimonium bromide in concentrations ranging from 2 to 17.5 Percent. A number of these agents have caused irritant or allergic contact dermatitis.

First aid
 
   Ingestion
Do not induce emesis - dilution: following ingestion and/or prior to gastric evacuation, immediately dilute with 4 to 8 ounces (120 to 240 ml) of milk or water (not to exceed 15 ml/kg in a child). The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing, wash exposed area with copious amounts of water. A physician should examine the area if irritation or pain persists.
   Eyes
Eye exposure results in mild discomfort (0.1 Percent solution) to very serious corneal damage (1 to 10 percent solution) depending on the concentration. Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
HS Code
2923 90 00