Zingerone

  • gingerone
  • 4-hydroxy-3-methoxybenzylacetone
  • 4-(4-Hydroxy-3-methoxyphenyl)-2-butanone
  • (4-Hydroxy-3-methoxyphenyl)ethyl methyl ketone
  • 3-Methoxy-4-hydroxybenzylacetone
  • 4-(3-methoxy-4-hydroxyphenyl)-2-butanone
Formula
C11H14O3
Structure
Description
Crystals from acetone, petroleum ether, ether plus petroleum ether strong, pungent odor reminiscent of ginger.
Uses
Flavor ingredient.

Registry Numbers and Inventories.
CAS
122-48-5
EC (EINECS/ELINCS)
204-548-3
RTECS
EL8900000
RTECS class
Natural Product; Primary Irritant
UN (DOT)
1325
Merck
12,10301
Beilstein/Gmelin
2051099
Beilstein Reference
4-08-00-01866
Canada DSL/NDSL
DSL
US TSCA
Listed
Austrailia AICS
Listed
New Zealand
Listed

Properties.
Formula
C11H14O3
Formula mass
194.23
Melting point, °C
40
Boiling point, °C
126 (0.4 torr)
Density
1.138-1.139 g/cm3 (25 C)
Solubility in water
Insoluble

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Make no contact with the spilled material. ELIMINATE all ignition sources and ground all equipment. With clean shovel place material into clean, dry container and cover loosely; move containers from spill area.
Stability
No data.

Fire.
Fire fighting
Small Fires: Dry chemical, carbon dioxide, sand, earth, water spray or regular foam. Large Fires: Water spray, fog or regular foam.
Fire potential
Flammable/combustible material. May be ignited by friction, heat, sparks or flames.
Combustion products
Fire may produce irritating and/or toxic gases.

Health.
Exposure effects
Limited studies have generally documented little or no effect of ketones on reproduction in experimental animals. Human data is lacking. 2,5-Hexanedione has an effect on spermatogenesis in male experimental animals.
   Ingestion
Nausea and vomiting may occur.
   Inhalation
Ingestion of significant amounts may cause respiratory depression. Pulmonary aspiration may result in chemical pneumonitis.
   Skin
Skin exposure to the liquid or vapor may result in dermatitis and paresthesias of affected areas. Contact urticaria has also been reported.
   Eyes
See Skin.

First aid
 
   Ingestion
Seek medical assistance.
   Inhalation
Move victim to fresh air. Apply artificial respiration if victim is not breathing. Administer oxygen if breathing is difficult.
   Skin
Remove and isolate contaminated clothing and shoes. In case of contact with substance, immediately flush with running water for at least 20 minutes. Wash skin with soap and water.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1325
Response guide
Hazard class
4.1
Packing Group
II; III