Zirconium picramate

  • Zirconium, tetrakis(2-amino-4,6-dinitrophenolato)-
  • Phenol, 2-amino-4,6-dinitro-, zirconium complex
Formula
C24H16N12O20.Zr
Structure
Description
A slurry or sludge of yellow crystals.
Uses
Medication.

Registry Numbers and Inventories.
CAS
63868-82-6
RTECS
TJ7860000
RTECS class
Other
UN (DOT)
1517
Beilstein/Gmelin
NA

Properties.
Formula
C24H16N12O20Zr
Formula mass
883.74

Hazards and Protection.
Storage
Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition sources and untrained individuals. Secure and label area. Protect containers/cylinders from physical damage.
Handling
All chemicals should be considered hazardous. Avoid direct physical contact. Use appropriate, approved safety equipment. Untrained individuals should not handle this chemical or its container. Handling should occur in a chemical fume hood.
Protection
Wear appropriate protective gloves, clothing and goggles.
Respirators
Wear positive pressure self-contained breathing apparatus (SCBA).
Small spills/leaks
Keep sparks, flames, and other sources of ignition away. Keep material out of water sources and sewers. Keep spilled material wet. Do not attempt to sweep up dry material.
Stability
No data.
Incompatibilities
May react vigorously with reducing materials.
Decomposition
When heated to decomposition it emits tox fumes of nitrogen oxides.

Fire.
Fire fighting
Dangerously explosive. Flood with water. Cool all affected containers with flooding quantities of water. Apply water from as far a distance as possible.
Fire potential
Flammable/combustible material.
Hazards
May be ignited by heat, sparks or flames. DRIED OUT material may explode if exposed to heat, flame, friction or shock; Treat as an explosive. Keep material wet with water or treat as an explosive. Runoff to sewer may create fire or explosion hazard. MAY EXPLODE AND THROW FRAGMENTS 1600 meters (1 MILE) OR MORE IF FIRE REACHES CARGO.
Combustion products
Fire may produce irritating, corrosive and/or toxic gases.

Health.
Exposure effects
Experimental animals exposed to massive doses have developed CNS depression. Two individuals administered 50 milligrams of zirconium malate intravenously developed vertigo. Small fractions of zirconium were absorbed in female rats by the oral route, and the metal seemed to concentrate in the ovaries and produce hypervascularization. <br>In mice, offspring of clams who received zirconium during pregnancy had long-lasting behavioral changes. <br>Zirconium is found in newborn rats. <br>In rats, zirconium appears in the breast milk.
   Ingestion
Ingestion of certain zirconium salts may cause irritant or caustic effects.
   Inhalation
Pulmonary abnormalities have not been demonstrated in workers with zirconium fume exposure for 1 to 5 years.
   Skin
Dermal exposure to zirconium in topical poison ivy medications and deodorants has caused subcutaneous granulomas, probably due to a hypersensitivity reaction.
   Eyes
Zirconium and its compounds are eye irritants.

First aid
 
   Ingestion
The possible benefit of early removal of some ingested material by cautious gastric lavage must be weighed against potential complications of bleeding or perforation. Activated charcoal activated charcoal binds most toxic agents and can decrease their systemic absorption if administered soon after ingestion. Activated charcoal: administer charcoal as a slurry (240 ml water/30 g charcoal). Usual dose: 25 to 100 g in adults/adolescents.
   Inhalation
Move patient to fresh air. Monitor for respiratory distress. If cough or difficulty breathing develops, evaluate for respiratory tract irritation, bronchitis, or pneumonitis. Administer oxygen and assist ventilation as required. Treat bronchospasm with beta2 agonist and corticosteroid aerosols.
   Skin
Remove contaminated clothing and wash exposed area thoroughly with soap and water. A physician should examine the area if irritation or pain persists. Treat dermal irritation or burns with standard topical therapy. Patients developing dermal hypersensitivity reactions may require treatment with systemic or topical corticosteroids or antihistamines.
   Eyes
Irrigate exposed eyes with copious amounts of tepid water for at least 15 minutes. If irritation, pain, swelling, lacrimation, or photophobia persist, the patient should be seen in a health care facility.

Transport.
UN number
1517
Response guide
Hazard class
4.1
Packing Group
I
 
Std. Transport #
4917195