Zopiclone

  • Amoban
  • Amovane
  • Imovane
  • 27267 R.P.
  • 1-Piperazinecarboxylic acid, 4-methyl-, 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H- pyrrolo(3,4-b)pyrazin-5-yl ester
  • 4-Methyl-1-piperazinecarboxylic acid 6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester
Formula
C17H17ClN6O3
Structure
Uses
Benzodiazepine receptor agonist

Registry Numbers and Inventories.
CAS
43200-80-2
EC (EINECS/ELINCS)
256-138-9
20/21/22 36/37/38 62
RTECS
TL1425000
RTECS class
Mutagen; Reproductive Effector
Merck
12,10324
Beilstein/Gmelin
768704
Beilstein Reference
6-26
New Zealand
Listed

Properties.
Formula
C17H17ClN6O3
Formula mass
388.81
Melting point, °C
175
Boiling point, °C
581
Vapor pressure, mmHg
2E-13 (25 C)
Density
1.47 g/cm3
Solubility in water
Slightly soluble
pKa/pKb
6.88 (pKb)
Heat of vaporization
86.9 kJ/mol

Hazards and Protection.
Storage
Keep tightly closed.
Protection
Wear respirator, chemical safety goggles, rubber boots, and heavy rubber gloves.
Small spills/leaks
Sweep up, place in a bag and hold for waste disposal. Avoid raising dust. Ventilate area and wash spill site after material pickup is complete.
Stability
Stable at normal temperatures and pressures.
Incompatibilities
Oxidizing agents.
Decomposition
Carbon monoxide, Carbon dioxide, Nitrogen oxides, Hydrogen chloride gas.

Fire.
Flash Point,°C
305
Fire fighting
Extinguish using Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Wear self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Hazards
Emits toxic fumes under fire conditions.
Health
2
 
Flammability
0
 
 
Reactivity
0
 

Health.
Exposure effects
Harmful. Possible risk of impaired fertility. Harmful by inhalation, in contact with skin and if swallowed. Irritating to eyes, respiratory system and skin. Reproductive hazard. Target organ(s): Central nervous system.
   Ingestion
Harmful if swallowed.
   Inhalation
Harmful if inhaled. Material is irritating to mucous membranes and upper respiratory tract.
   Skin
Causes skin irritation. Harmful if absorbed through skin.
   Eyes
Causes eye irritation.

First aid
 
   Ingestion
If swallowed, wash out mouth with water provided person is conscious. Call a physician.
   Inhalation
If inhaled, remove to fresh air. If not breathing give artificial respiration. If breathing is difficult, give oxygen.
   Skin
In case of skin contact, flush with copious amounts of water for at least 15 minutes. Remove contaminated clothing and shoes. Call a physician.
   Eyes
In case of contact with eyes, flush with copious amounts of water for at least 15 minutes. Assure adequate flushing by separating the eyelids with fingers. Call a physician.

Transport.